Prehospital Reversal of Warfarin-Related Coagulopathy in Intracerebral Hemorrhage in a Mobile Stroke Treatment Unit

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Prehospital reversal of warfarin-related coagulopathy in intracerebral hemorrhage in a mobile stroke treatment unit.

W arfarin-related intracerebral hemorrhage (ICH) accounts for 15% to 20% of all intraparenchymal hemorrhages and is associated with a much higher mortality than spontaneous ICH. 1 Although rapid (ie, within 2 hours of onset) reversal of warfarin effect has been advocated, 2,3 significant delays in initiation of therapy and correction of international normalized ratio are common. A mobile stroke...

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Timing of fresh frozen plasma administration and rapid correction of coagulopathy in warfarin-related intracerebral hemorrhage.

BACKGROUND AND PURPOSE Anticoagulation-related intracerebral hemorrhage (ICH) is often fatal, and rapid reversal of anticoagulation is the most appealing strategy currently available for treatment. We sought to determine whether particular emergency department (ED) interventions are effective in reversing coagulopathy and improving outcome. METHODS Consecutive patients with warfarin-related I...

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Warfarin-associated intracerebral hemorrhage after ischemic stroke.

BACKGROUND AND PURPOSE The aim was to investigate the risk of intracerebral hemorrhage (ICH) in patients with ischemic stroke taking warfarin and whether this risk changed over time. METHODS Between 2001 and 2008, the Swedish Stroke Register registered 12,790 patients with ischemic stroke discharged on warfarin. The patients was studied in two 4-year periods (inclusion 2001-2004: follow-up un...

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Predictors of outcome in warfarin-related intracerebral hemorrhage.

BACKGROUND Intracerebral hemorrhage (ICH) associated with warfarin sodium therapy is becoming more common as the use of this medication increases in the aging population. OBJECTIVE To delineate factors associated with early mortality, determine variables responsible for poor functional outcome, and evaluate possible reasons for expansion of hemorrhage and associated parenchymal edema. DESIG...

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Introduction:The use of anticoagulant and ant platelet medications, especially warfarin and clopidogrel, is on a growing trend. Warfarin usage is commonly accompanied with hemorrhagic complications resulting in a noticeable mortality rate. Patient's ant coagulated with warfarin suffers from intracranial hemorrhage after a head injury. Materials and Methods: For the purpose of the study, the rel...

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ژورنال

عنوان ژورنال: Stroke

سال: 2015

ISSN: 0039-2499,1524-4628

DOI: 10.1161/strokeaha.115.008483